If you read instruction on how to set up mod_mono with Apache here: http://www.mono-project.com/FAQ:_ASP.NET do not forget to read a little bit more about it here: ImprovingModMono - http://www.mono-project.com/ImprovingModMono Because 'MonoDebug' directive really crash all my settings and took me whole day to figure it. If you have this command in your configurations files - just commant it and then everything back to normal